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KMID : 0985420080300010151
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Laboratory Medicine and Quality Assurance
2008 Volume.30 No. 1 p.151 ~ p.166
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Annual Report on External Quality Assessment in Metabolic Disorders in Korea (2007)
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Song Jung-Han
Min Won-Ki
Kim Jung-Ho
Kim Jong-Won
Kwon Kye-Chul
Lee Soo-Youn
Lee Eun-Hee
Choi Tae-Yoon
Jun Sun-Hee
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Abstract
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Two trials of external quality assessment for the newborn screening tests of inborn errors of metabolism including PKU screening, TSH, T4 (total/free), galactosemia screen, maple syrup urine disease screen and homocytinuria screen, were performed in 2007. Total 20 specimens for the newborn screening tests were distributed to 16 laboratories. The response rate was 100%. All the control materials were sent as filter paper forms. The mean, SD, CV, median and range were analyzed. From this trial, the proficiency tests for newborn screening tests using tandem mass spectrometry (MS/MS) were included as routine quality assessment. Participants results for amino acids, acylcarnitine and their cutoff values were analyzed. In addition, the trial of external quality assessment for glycohemoglobin (HbA1c) was first started in 2007. Two samples prepared from normal whole blood and commercially available abnormal control materials, were distributed to 246 laboratories and the response rate was 93%. Statistical data such as mean, SD and CV were provided for peer groups.
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KEYWORD
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External Quality Assessment, Metabolic Disorders, Newborn screening, Tandem mass spectrometry, HbA1c
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